Innovative bioreactors.

Innovative Disposable Bioreactors For Membrane Protein Production Based on the Tide Principle

Innovative, non-stirred bioreactors in scales from milliliters up to 1000 liters for suspension cultures of cells using disposable bags and containers--a Swiss contribution.

Innovative mixing principles in bioreactors, for example using the rocking of a platform to induce a backwards and forwards 'wave', or using orbital shaking to generate a 'wave' that runs round in a cylindrical container, have proved to be successful for the suspension cultures of cells, especially when combined with disposable materials. This article presents an overview of the engineering cha...

Enhanced Biological Phosphorus Removal within Membrane Bioreactors

Several Membrane Bioreactor (MBR) facilities have been constructed with the intent of providing Enhanced Biological Phosphorus Removal (EBPR), and several additional such plants are being designed and constructed. Full-scale plant information is now available for process designers to better understand the unique design and operating issues associated with the incorporation of EBPR designs in MB...

Do There Exist Innovative Perspectives in Tissue Engineering-Based Ligament Reconstruction?

Reconstruction of musculoskeletal tissues requires innovative strategies, which need to be developed by experimental research. As much as possible the application of tailored and optimized in vitro models based on human-derived cell sources should be expanded to substitute and scale down animal experiments and to collect sufficient information for the concerted selection of the most suitable an...

3D microfabricated bioreactor with capillaries.

We present in this paper the implementation of an innovative three dimensional (3D) microfabrication technology coupled with numerical simulation to enhance the mass transport in 3D cell culture. The core of this microfabrication technology is a high-resolution projection micro stereolithography (PmicroSL) using a spatial light modulator as a dynamic mask which enables a parallel fabrication of...